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Rhexan International is a US-based importer and distributor of clotrimazole USP, a broad-spectrum antifungal API sourced from FDA-registered manufacturers including Guangzhou Hanpu Pharmaceutical Co., Ltd. With CAS number 23593-75-1 and molecular formula C₂₂H₁₇ClN₂, clotrimazole is widely used in topical antifungal pharmaceuticals, OTC products, veterinary formulations, and compounding applications. We supply this micronized material to pharmaceutical manufacturers, specialty compounders, and consumer health companies across the United States.
Clotrimazole Specifications
| Property | Specification |
|---|---|
| Chemical Name | Clotrimazole (Micronized) |
| CAS Number | 23593-75-1 |
| Molecular Formula | C₂₂H₁₇ClN₂ |
| Grade | USP2024 |
| Appearance | Crystalline white powder |
| Assay (dried basis) | 98%–102% (Result: 99.95%) |
| Related Compound A | ≤0.5% |
| Imidazole | ≤0.5% |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤0.001% |
| Residual Solvents | Benzene ≤2ppm; Acetonitrile ≤410ppm |
| Microbial Limits | TPC <1,000 cfu/g; No pathogens |
| Particle Size | 90% pass 10 micron (micronized) |
| Identification | Positive (IR <197>, HPLC) |
| Manufacturer | Guangzhou Hanpu Pharmaceutical Co., Ltd |
| Packaging | 25 kg/Drum |
Applications of Clotrimazole
- Topical Antifungal Pharmaceuticals: Active ingredient in prescription and OTC antifungal creams, lotions, and solutions for treatment of athlete’s foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris).
- Vaginal Antifungal Products: Used in vaginal creams and suppositories for treatment of vulvovaginal candidiasis (yeast infections).
- Veterinary Formulations: Antifungal active for veterinary topical and otic preparations treating dermatophytosis and candidiasis in companion animals.
- Compounding Pharmacies: Supplied to licensed compounding pharmacies for customized antifungal preparations in human and veterinary applications.
- OTC Consumer Health: Finished product manufacturers formulating clotrimazole 1% and 2% topical OTC antifungal products.
Why Source Clotrimazole from Rhexan?
- USP-Grade, Fully Documented: Supplied with Certificate of Analysis confirming conformance to USP2024 standards, including full impurity and microbiological testing.
- Micronized Particle Size: 90% of particles pass 10 micron — optimized for topical formulation performance and uniform dispersion.
- FDA-Registered Manufacturer: Sourced from Guangzhou Hanpu Pharmaceutical Co., Ltd, a GMP-certified producer with FDA-registered facilities.
- Reliable Supply Chain: Established import logistics with consistent inventory to support your production schedule.
- Expert Support: Our team assists with regulatory questions, documentation requests, and grade selection for your specific application.
Looking for a reliable clotrimazole supplier for your pharmaceutical, veterinary, or compounding application? Contact Rhexan International today for pricing, lead times, and a Certificate of Analysis.