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Rhexan International is a trusted cyclosporine USP supplier and US-based importer of cyclosporine, a cyclic polypeptide immunosuppressant derived from the fungus Tolypocladium inflatum. With CAS number 59865-13-3, cyclosporine USP is sourced from GMP-certified manufacturers including Joyang Laboratories. We supply this material to pharmaceutical manufacturers, transplant medicine formulators, and specialty compounders across the United States.
CYCLOSPORINE USP SPECIFICATIONS
| Product Name | Cyclosporine |
| Grade | USP |
| CAS Number | 59865-13-3 |
| Appearance | White powder |
| Assay (dried basis) | 98.5% – 101.5% (Result: 99.6%) |
| Loss on Drying | ≤2.0% (Result: 0.4%) |
| Heavy Metals | ≤20 ppm (Result: <20 ppm) |
| Any Individual Impurity | ≤0.7% (Result: 0.3%) |
| Total Impurities | ≤1.5% (Result: 0.8%) |
| Appearance of Solution | Clear, not more intensely colored than reference solution Y5 |
| Residual Solvents – Acetone | ≤1000 ppm (Result: 33 ppm) |
| Residual Solvents – Petroleum Ether | ≤100 ppm (Result: 1 ppm) |
| TAMC (Microbial) | ≤1000 cfu/g (Result: <10 cfu/g) |
| TYMC (Microbial) | ≤100 cfu/g (Result: <10 cfu/g) |
| Escherichia coli | None (Result: Not Detected) |
| Manufacturer | Joyang Laboratories (GMP certified) |
| Expiration Date | March 6, 2029 |
| Storage | Preserve in tight, light-resistant containers; store below 25°C (range 15°C–30°C) |
| Packaging | 20 kg/drum |
CYCLOSPORINE USP SUPPLIER: KEY APPLICATIONS
- Organ Transplantation: Foundational immunosuppressant for prevention of rejection in kidney, liver, heart, and bone marrow transplant patients.
- Topical Ophthalmic: Active ingredient in ophthalmic emulsions for treatment of chronic dry eye disease and ocular inflammation.
- Dermatology: Used in systemic and topical formulations for treatment of severe psoriasis, atopic dermatitis, and other immune-mediated skin conditions.
- Compounding Pharmacies: Supplied to licensed compounding pharmacies for custom oral and topical immunosuppressant preparations.
- Pharmaceutical Manufacturing: Used by specialty manufacturers producing oral capsule, oral solution, and injectable formulations for transplant and autoimmune indications.
REQUEST A QUOTE
Rhexan International supplies cyclosporine USP to qualified buyers in the pharmaceutical and compounding industries. All material is sourced from GMP-certified manufacturers and supported by a full Certificate of Analysis. Contact us to request a quote or technical documentation.