← Active Pharmaceutical Ingredients
Rhexan International is a trusted tacrolimus USP supplier and US-based importer of tacrolimus, a macrolide immunosuppressant produced by fermentation of Streptomyces tsukubaensis. With CAS number 109581-93-3, tacrolimus USP is sourced from GMP-certified manufacturers including Joyang Laboratories. We supply this material to pharmaceutical manufacturers, transplant medicine formulators, and specialty compounders across the United States.
TACROLIMUS USP SPECIFICATIONS
| Product Name | Tacrolimus |
| Grade | USP |
| CAS Number | 109581-93-3 |
| Appearance | White crystalline powder, odorless |
| Assay (anhydrous, solvent-free basis) | 98.0% – 102.0% (Result: 99.8%) |
| Optical Rotation | -110° to -115° (Result: -112°) |
| Water | ≤4.0% (Result: 2.1%) |
| Heavy Metals | ≤10 ppm (Result: <10 ppm) |
| Residue on Ignition | ≤0.1% (Result: 0.0%) |
| Total Impurities | ≤1.0% (Result: 0.1%) |
| Residual Solvents – Ethanol | ≤2000 ppm (Result: 30 ppm) |
| TAMC (Microbial) | ≤1000 cfu/g (Result: <10 cfu/g) |
| TYMC (Microbial) | ≤100 cfu/g (Result: <10 cfu/g) |
| Manufacturer | Joyang Laboratories (GMP certified) |
| Expiration Date | June 3, 2028 |
| Storage | Preserve in tight containers; store below 25°C |
| Packaging | 1500 g/container |
TACROLIMUS USP SUPPLIER: KEY APPLICATIONS
- Organ Transplantation: Primary immunosuppressant for prevention of rejection in kidney, liver, and heart transplant patients.
- Topical Dermatology: Active ingredient in topical formulations (ointments and creams) for treatment of moderate-to-severe atopic dermatitis (eczema) in patients unresponsive to conventional therapies.
- Compounding Pharmacies: Supplied to licensed compounding pharmacies for custom immunosuppressant and dermatological preparations.
- Pharmaceutical Manufacturing: Used by specialty pharmaceutical manufacturers producing oral capsule and injectable formulations for transplant medicine.
REQUEST A QUOTE
Rhexan International supplies tacrolimus USP to qualified buyers in the pharmaceutical and compounding industries. All material is sourced from GMP-certified manufacturers and supported by a full Certificate of Analysis. Contact us to request a quote or technical documentation.